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  • The World Health Organization clinical decision rule was specific but not sensitive for predicting group A β haemolytic streptococcus in children with pharyngitis

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Clinical prediction guide
The World Health Organization clinical decision rule was specific but not sensitive for predicting group A β haemolytic streptococcus in children with pharyngitis

https://doi.org/10.1136/ebm.11.4.122

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    Rimoin AW, Hamza HS, Vince A, et al. Evaluation of the WHO clinical decision rule for streptococcal pharyngitis. Arch Dis Child 2005;90:1066–70.
    OpenUrlAbstract/FREE Full Text

    
 
 Q In children with complaints of sore throat, how accurate is the World Health Organization (WHO) clinical decision rule for predicting group A β haemolytic streptococcus (GABHS) on throat culture?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Infectious disease ★★★★★★☆ Paediatrics ★★★★☆☆☆

    METHODS

    Embedded ImageDesign:

    prospective cohort study to validate the previously developed WHO clinical decision rule for GABHS pharyngitis.

    Embedded ImageSetting:

    3 urban paediatric outpatient clinics in Rio de Janiero, Brazil; Cairo, Egypt; and Zagreb, Croatia.

    Embedded ImagePatients:

    1810 children aged 2–12 years (mean age 5 y, 57% boys) with complaints of sore throat (among 2255 with acute respiratory infections). Exclusion criteria were antibiotic use (oral within 3 d or intramuscular within 28 d), history of rheumatic fever or heart disease, or illness requiring hospital admission. …

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    Footnotes

    • For correspondence: Dr A W Rimoin, UCLA School of Public Health, Los Angeles, CA, USA. arimoin{at}ucla.edu

    • Sources of funding: USAID and World Health Organization.