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Q Is computed tomographic colonography (CTC) an accurate test for the diagnosis of colorectal polyps and cancer?
Clinical impact ratings Internal medicine ★★★★★★☆ Gastroenterology ★★★★★☆☆ Oncology ★★★★★☆☆ Surgery—colorectal ★★★★★☆☆
METHODS
Data sources:
Medline (1994–2003); EMBASE/Excerpta Medica, Science Citation Index, Cochrane Controlled Trials Register, and relevant key journals (1994 to May 2003); and reference lists of included studies.
Study selection and assessment:
full reports in any language of cohort studies that evaluated the use of CTC for the detection of colorectal polyps; used full bowel preparation, prone and supine images, helical scanners, and commercially available software; and blinded interpreters to the results of the reference standard (colonoscopy or surgical findings). Studies with <30 patients or a high proportion of patients with known abnormality were excluded. 24 studies (n = 4181) met the selection criteria. …
Footnotes
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For correspondence: Dr S Halligan, University College Hospital, London, UK. steve{at}halligan9.fsnet.co.uk
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Source of funding: European Association of Radiology.