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Review: antibiotic therapy leads to slightly earlier recovery in acute bacterial conjunctivitis

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 Q In patients with acute bacterial conjunctivitis, is antibiotic therapy better than placebo?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Emergency medicine ★★★★★★★ Infectious disease ★★★★★☆☆ Paediatrics ★★★★★☆☆

METHODS

Embedded ImageData sources:

Medline, EMBASE/Excerpta Medica, and PubMed (all to January 2006); Cochrane Central Register of Controlled Trials (including Cochrane Eyes and Vision Group Trials Register) (issue 4, 2005); SIGLE (up to March 2005); National Research Register (issue 4, 2005); reference lists; authors and investigators of relevant studies; Science Citation Index; and pharmaceutical companies.

Embedded ImageStudy selection and assessment:

double blind randomised controlled trials (RCTs) that compared any form of antibiotic treatment (including topical, systemic, and combination) with placebo for acute bacterial conjunctivitis. 5 RCTs (n = 1034, >1 mo of age) met the selection criteria; their interventions …

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