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Nurse-led cognitive behaviour therapy improved insight and reduced negative symptoms and readmissions in schizophrenia

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 Q In patients with schizophrenia, does brief cognitive behaviour therapy (CBT) delivered by mental health nurses reduce symptoms, recovery time, and readmissions at 1 year?

Clinical impact ratings GP/FP/Mental health ★★★★★★☆ Psychiatry ★★★★★★☆

METHODS

Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:

{concealed*}.

Embedded ImageBlinding:

blinded (data collectors}.*

Embedded ImageFollow up period:

1 year.

Embedded ImageSetting:

6 sites in the UK.

Embedded ImagePatients:

422 patients {18–65 years of age} {mean age 40 y, 77% men} who had an ICD-10 diagnosis of schizophrenia and were receiving treatment from psychiatry secondary sources. Patients were excluded if they were in the process of active relapse or had a primary diagnosis of substance or alcohol dependence, organic brain disease, or severe learning disability.

Embedded ImageIntervention:

CBT {n = 257} or usual care as organised by a community key worker, with an offer of CBT at the end of the study period {n = 165} …

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