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Herbal supplements did not relieve vasomotor symptoms of menopause in women

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 Q Do herbal supplements relieve vasomotor symptoms of menopause in women?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆

METHODS

Embedded ImageDesign:

randomised placebo controlled trial (Herbal Alternatives for Menopause Trial [HALT]).

Embedded ImageAllocation:

concealed.*

Embedded ImageBlinding:

blinded (clinicians, participants, {data collectors, and outcome assessors}).*

Embedded ImageFollow up period:

12 months.

Embedded ImageSetting:

Washington State, USA.

Embedded ImagePatients:

351 women 45–55 years of age (mean age 52 y, 93% white) who were in menopausal transition or postmenopausal with ⩾2 vasomotor symptoms per day for 2 weeks (⩾6 moderate to severe symptoms). Exclusion criteria included contraindications to hormone therapy (HT), use of HT or oral contraceptives in the past 3 months, use of herbal medicines in the past month, bilateral oophorectomy, or history of breast cancer.

Embedded ImageIntervention:

black cohosh (Actaea racemosa or Cimicifuga racemosa), 160 …

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