Article Text

PDF
Review: drugs for mild to moderate hypertension in pregnancy reduce the risk of severe hypertension but not pre-eclampsia

Statistics from Altmetric.com


 
 Q In pregnant women with mild to moderate hypertension, what are the benefits and risks of antihypertensive (anti-HT) drugs? Is one type of anti-HT drug better than another?

Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ GP/FP/Obstetrics ★★★★★★☆ Internal medicine ★★★★★★☆ Nephrology ★★★★★★☆ Obstetrics ★★★★★★☆

METHODS

Embedded ImageData sources:

Cochrane Pregnancy and Childbirth Group’s Trials Register (March 2006); Cochrane Central Register of Controlled Trials (2005, issue 3); and Medline, LILACS, and EMBASE/Excerpta Medica (to November 2005).

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) that evaluated any anti-HT drug (compared with placebo or no anti-HT drug [control] or another type of anti-HT drug) for mild to moderate hypertension during pregnancy. Quasi-randomised studies and those involving treatment for <7 days were excluded. 46 RCTs met the selection criteria: 28 RCTs compared anti-HT drugs with control (n = 3200) and 19 RCTs compared 2 types of anti-HT drugs (n = 1282).

Embedded ImageOutcomes:

severe hypertension, pre-eclampsia, fetal or neonatal death, preterm …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.