Article Text

PDF
Patients with lone atrial fibrillation had low risk of progression to permanent atrial fibrillation, death, congestive heart failure, and stroke

Statistics from Altmetric.com

P A Friedman

Dr P A Friedman, Mayo Clinic, Rochester, MN, USA; friedman.paul@mayo.edu

STUDY QUESTIONS

In patients newly diagnosed with lone atrial fibrillation (AF) and without structural heart disease, what is the risk of progression to permanent AF, congestive heart failure (CHF), stroke, and death? Which factors predict these outcomes?

STUDY DESIGN

Design:

inception cohort followed up for a median 26.8 years (range 2.5–42.2 y).

Setting:

Olmsted County, Minnesota, USA.

Patients:

76 patients <60 years of age (mean age 44 y, 78% men) with AF first documented by electrocardiography between 1950 and 1980. Patients were categorised into 3 AF types: (i) paroxysmal, if terminated spontaneously (n = 34); (ii) persistent, if it could be terminated by medication or electrical intervention (n = 37); and (iii) permanent, if sinus rhythm could not be restored or maintained despite intervention (n = 5).

Exclusion criteria were coronary artery or valvular disease, cardiomyopathy, cardiomegaly, pre-excitation syndrome, history of …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.