Article Text

Review: calcium supplementation during pregnancy reduces the risk of pre-eclampsia

Statistics from

Dr G J Hofmeyr

Correspondence to: Dr G J Hofmeyr, University of the Witwatersrand, East London, South Africa;


Does calcium supplementation during pregnancy reduce the risk of high blood pressure, pre-eclampsia, and related maternal and neonatal adverse outcomes?


Selected studies compared calcium supplementation (⩾1 g/d) with placebo during pregnancy (starting at <35 wks’ gestation) for prevention of hypertensive disorders of pregnancy. Outcomes were high blood pressure; pre-eclampsia; maternal death or serious morbidity; haemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome; preterm birth; stillbirth or neonatal death; and admission to neonatal intensive care unit.


Cochrane Pregnancy and Childbirth Group trials register (March 2006) and Cochrane Central Register of Controlled Trials …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.