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Y P de Jong
Dr Y P de Jong, Isala Klinieken, Zwolle, The Netherlands; firstname.lastname@example.org
randomised, placebo controlled, non-inferiority trial.
single hospital in Zwolle, the Netherlands.
210 patients >40 years of age (mean age 71 y, 75% men) who were admitted to hospital for chronic obstructive pulmonary disease (COPD) exacerbation (history of increased breathlessness and >1 of the following for ⩾24 hours: increased cough frequency or severity, increased sputum volume or purulence, and increased wheeze), had a history of ⩾10 pack-years cigarette smoking, and evidence of airflow limitation (forced expiratory volume in 1 second [FEV1]/forced vital capacity ratio <70% and FEV1 <80% predicted). Exclusion criteria included very severe exacerbation of …
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