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Intensive glucose control increased mortality and did not prevent cardiovascular events in type 2 diabetes

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R P Byington

Dr R P Byington, Wake Forest University School of Medicine, Winston-Salem, NC, USA; bbyingto@wfubmc.edu

STUDY DESIGN

Design:

randomised controlled trial (Action to Control Cardiovascular Risk in Diabetes [ACCORD]).

Allocation concealment:

concealed.*

Blinding:

blinded (outcome adjudication committee and laboratory staff).*

STUDY QUESTION

Setting:

77 centres in the USA and Canada.

Patients:

10 251 patients 40–79 years of age (mean age 62 y, 61% …

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