Lifestyle interventions reduced the long-term risk of diabetes in adults with impaired glucose tolerance
Dr G Li, China-Japan Friendship Hospital, Beijing, China; email@example.com
cluster randomised controlled trial (China Da Qing Diabetes Prevention Outcomes Study [CDQDPOS]).
blinded (data collectors and outcome adjudicators).*
33 clinics in Da Qing, China.
577 adults (mean age 46 y, 54% men) with impaired glucose tolerance.
1 of 3 group-based lifestyle interventions for 6 years: diet (to increase vegetable intake, lower alcohol and sugar intake, and reduce weight if indicated), exercise (to increase leisure-time physical activity), or diet plus exercise (n = 438, 3 groups pooled); or usual care (n = 138).
diabetes, cardiovascular disease (CVD) event (myocardial infarction, stroke, sudden death, or amputation), CVD mortality, and all-cause mortality.
94–98% (intention-to-treat analysis). …