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Benefits of tight blood pressure control to prevent diabetes complications were not sustained

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R R Holman

Dr R R Holman, Diabetic Trials Unit, Oxford, UK; rury.holman@dtu.ox.ac.uk

STUDY DESIGN

Design:

randomised controlled trial (Hypertension in Diabetes Study) within the UK Prospective Diabetes Study (UKPDS). Current Controlled Trials ISRCTN75451837.

Allocation:

{concealed}*.†

Blinding:

blinded (outcome adjudication committee).†

STUDY QUESTION

Setting:

{20}* centres in the UK.

Patients:

1148 patients {mean age 56 y, 56% men}* with type 2 diabetes who were already participating in the UKPDS and had hypertension. Exclusion criteria included …

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