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Therapeutics
Review: an early invasive strategy has similar benefits in men and women with NSTEMI or unstable angina

https://doi.org/10.1136/ebm.14.1.19

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    M O’Donoghue

    Dr M O’Donoghue, Brigham and Women’s Hospital, Boston, MA, USA; modonoghue@partners.org

    QUESTION

    In patients with non–ST-segment elevation myocardial infarction (NSTEMI) or unstable angina, does an early invasive strategy, compared with a conservative strategy, have similar benefits in men and women?

    REVIEW SCOPE

    Included studies compared an early invasive strategy (immediate coronary angiography followed by revascularisation if appropriate) with a conservative strategy (primary pharmacological management with coronary angiography reserved for patients with recurrent ischaemia) in patients with NSTEMI or unstable angina. Studies were excluded if fibrinolytic therapy was administered to all patients or coronary angiography was required before enrolment. Outcomes were death, non-fatal MI, hospital readmission for acute coronary syndrome, and a composite of these 3 outcomes.

    REVIEW METHODS

    Medline and Cochrane Library (to …

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    Footnotes

    • Source of funding: no external funding.