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5-day and 3-day oral prednisolone did not differ for asthma control in children who had acute asthma exacerbations

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A B Chang

Professor A B Chang, Queensland Children's Respiratory Centre, Brisbane, Queensland, Australia; annechang@ausdoctors.net

STUDY DESIGN

Design:

randomised controlled trial. Australian Clinical Trials Registry ACTRN012605000305628.

Allocation:

concealed.*

Blinding:

blinded (children, parents, and healthcare providers).*

STUDY QUESTION

Setting:

emergency departments (EDs) in 3 hospitals in Queensland, Australia.

Patients:

201 children 2–15 years of age (mean age 5 y, 60% boys) who presented to the ED between 7:30 am and 5 pm with acute exacerbation (needing >1 dose of salbutamol in 1 h) of asthma (>2 episodes of wheeze or dyspnoea with decreased respiratory rate and work of breathing in response to salbutamol) and were not admitted to hospital. Exclusion criteria were underlying respiratory disease, cerebral …

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