You are here

Article Text

Article menu
Download PDFPDF
Therapeutics
Review: less than maximum doses of ACE inhibitors lower BP to near maximum levels in hypertension

https://doi.org/10.1136/ebm.14.2.49

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    B S Heran

    Dr B S Heran, University of British Columbia, Vancouver, BC, Canada; bsheran@ti.ubc.ca

    QUESTION

    In patients with primary hypertension, what is the dose-related efficacy of angiotensin converting enzyme (ACE) inhibitors for lowering blood pressure (BP)?

    REVIEW SCOPE

    Included studies compared ACE inhibitors with placebo in patients with BP ⩾140/90 mm Hg, measured BP at 3–12 weeks after treatment, and had ⩾3 weeks’ follow-up. Studies of patients taking other drugs affecting BP or having secondary hypertension due to renal failure were excluded. Outcomes included change in trough or peak BP at 3−12 weeks.

    REVIEW METHODS

    Medline and EMBASE/Excerpta Medica (to February 2007), Cochrane Library (2007, issue 1), and reference lists were searched for double-blind …

    View Full Text

    Footnotes

    • Source of funding: Canadian Institutes of Health Research.