Statistics from Altmetric.com
randomised controlled trial (Veterans Affairs Diabetes Trial [VADT]). ClinicalTrials.gov NCT00032487.
unclear allocation concealment.*
blinded (outcome assessors).*
20 sites in the USA.
1791 patients (mean age 60 y, 97% men) who had inadequate responses to maximum doses of an oral agent or insulin therapy. Exclusion criteria included glycated haemoglobin (HbA1c) concentration <7.5%, cardiovascular (CV) event in the past 6 months, advanced congestive heart failure (CHF), severe angina, body mass index (BMI) >40 kg/m2, serum creatinine concentration >1.6 mg/dl (141 µmol/l), and alanine aminotransferase concentration >3 times the upper normal limit.
intensive (n = 892) or standard glucose control (n = 899). Patients were given oral metformin plus rosiglitazone (BMI ⩾27 kg/m2) or oral glimepiride plus rosiglitazone (BMI <27 kg/m2). The intensive-control group …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.