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Self-monitored, home-based pulmonary rehab was non-inferior to outpatient, hospital-based rehab for COPD

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STUDY DESIGN

Design:

randomized controlled trial. ClinicalTrials.gov NCT00169897; ISRCTN32824512.

Allocation:

concealed.*

Blinding:

blinded {data collectors and analysts, outcome assessors, and safety committee}†.*

STUDY QUESTION

Setting:

10 centres in Canada.

Patients:

252 patients ⩾40 years of age (mean age 66 y, 56% men) who had stable chronic obstructive pulmonary disease (COPD; no change in medication or symptoms for ⩾ 4 wks), were current or former smokers of ⩾10 pack-years, had an FEV1 <70% of predicted value and FEV1–FVC ratio <0.70, and had a Medical Research Council (MRC) dyspnoea score ⩾2. Exclusion criteria included history of asthma, congestive left heart failure as primary disease, terminal disease, dementia, and uncontrolled psychiatric illness.

Intervention:

home-based exercise programme (n = 126) or outpatient, hospital-based exercise programme (n = 126). Both groups received an educational intervention in …

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