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Higher red blood cell distribution width was associated with increased risk of mortality in adults ⩾45 years of age

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Study question

Is a higher red blood cell distribution width (RDW) associated with increased risk of mortality in adults ⩾45 years of age?

Study design

Design:

cohort study.

Setting:

USA.

Participants:

8175 participants ⩾45 years of age (mean age 62 y, 54% women) from the civilian non-institutionalised population. 3 participants were excluded because insufficient information was available to search the National Death Index.

Risk factors:

RDW values were divided by quintiles (12.6–12.95%, 13–13.4%, 13.45–14.05%, and >14.05%). Results were adjusted for age, sex, and ethnicity.

Outcomes:

all-cause mortality.

Main results

Overall, 2428 (30%) participants died during 12 years of follow-up. Increasing RDW …

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