Intensive v standard glucose control in type 2 diabetes*
| Weighted event rates | At 2.9 to 10.1 years | |||
| Outcomes | Intensive | Standard | RRR (95% CI) | NNT (CI) |
| Non-fatal MI | 4.0% | 4.8% | 16% (6 to 25) | 131 (84 to 349) |
| CHD | 6.1% | 7.2% | 15% (9 to 20) | 93 (70 to 155) |
| Stroke | 3.1% | 3.4% | 10% (−1 to 20) | Not significant |
| RRI (CI) | NNH (CI) | |||
| Mortality | 8.5% | 8.4% | 2% (−12 to 19)† | Not significant |
| Heart failure | 4.4% | 4.1% | 8% (−10 to 29)† | Not significant |
-
*CHD, coronary heart disease; MI, myocardial infarction; other abbreviations defined in glossary. All results based on 5 trials (n = 33 040). RRR, RRI, NNT, NNH, and CI calculated from data in article using a random-effects model.
-
†Results were heterogeneous.
