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Several studies have assessed the accuracy of D-dimer testing in the diagnostic process for venous thromboembolism (VTE). A meta-analysis of the conventional D-dimer tests showed high sensitivities for enzymelinked fluorescent assay, microplate ELISA and latex quantitative assays, at the cost of lower specificity.1 These tests can therefore reliably exclude a VTE, but at the expense of more testing. In addition, a low pretest probability combined with a negative D-dimer test can safely exclude a VTE.2 Recently, newer point-of-care (POC) D-dimer tests have become available. Among the advantages of these tests …
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