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June 2010, Volume 15, Issue 3

[Author index]

Cover
  1. Therapeutics
  2. Treatment
  3. Prevalence
  4. Prognosis
  5. Purpose and procedure
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Issue information

[Front cover][Table of contents PDF][Front matter PDF]

Therapeutics

  • Women's Health Initiative randomised ontrolled trial: Combined estrogen plus progestin may reduce coronary heart disease risk after 5 years of use in postmenopausal women starting treatment within 10 years of menopause

    • S. Mitchell Harman
    Evid Based Med 2010;15:3 69-70 doi:10.1136/ebm1079

  • Randomised controlled trial: Intermittent preventive treatment of infants with mefloquine reduces risk of clinical malaria in areas of moderate malaria transmission and high resistance to sulphadoxine–pyrimethamine, but safety and tolerability issues need consideration

    • Rose McGready
    Evid Based Med 2010;15:3 71-72 doi:10.1136/ebm1039
    Editor's Choice

  • Randomised controlled trial: Pregabalin similar to lorazepam for alcohol withdrawal symptoms

    • Giovanni Addolorato,
    • Lorenzo Leggio
    Evid Based Med 2010;15:3 73 doi:10.1136/ebm1069

  • JUPITER randomised controlled trial: Rosuvastatin is similarly effective for primary prevention of cardiovascular disease in women as in men

    • Andrew Leventhal,
    • Erin D Michos
    Evid Based Med 2010;15:3 74-75 doi:10.1136/ebm1070

  • Cost-effectiveness analysis: Daily self-monitoring unlikely to be cost-effective in adults with type 2 diabetes not using insulin in Canada

    • Mayer B Davidson
    Evid Based Med 2010;15:3 75-76 doi:10.1136/ebm1062

  • Systematic review: Insufficient evidence to recommend routine adjunctive chest physiotherapy for adults with pneumonia

    • Michalis Agrafiotis
    Evid Based Med 2010;15:3 76-77 doi:10.1136/ebm1078

  • Randomised controlled trial: Nicotine patch plus lozenge gives greatest increases in abstinence from smoking rates at 6 months compared with placebo; smaller effects seen with nicotine patch alone, bupropion or nicotine lozenges alone or combined

    • David Gonzales
    Evid Based Med 2010;15:3 77-78 doi:10.1136/ebm1047

  • Systematic review: Combination therapy with long-acting β-agonists plus inhaled corticosteroids is no more effective than LABA monotherapy for mortality outcomes and severe exacerbations in moderate to very severe COPD and is associated with serious adverse effects

    • Peter Anthony Frith
    Evid Based Med 2010;15:3 78-79 doi:10.1136/ebm1050

  • Combined analysis of randomised controlled trials: Quadrivalent HPV vaccine administered to women who became pregnant during trials did not appear to adversely affect pregnancy outcome; however, use during pregnancy is not recommended

    • Karen Smith-McCune
    Evid Based Med 2010;15:3 80-81 doi:10.1136/ebm1066

  • Systematic review: No evidence that vaccinating health care workers prevents flu in elderly residents in long-term care facilities

    • G A van Essen
    Evid Based Med 2010;15:3 81-82 doi:10.1136/ebm1076

  • Systematic review: Most physical tests to identify lumbar-disc herniation show poor diagnostic performance when used in isolation, but findings may not apply to primary care

    • J N Alastair Gibson
    Evid Based Med 2010;15:3 82-83 doi:10.1136/ebm1071

  • Randomised controlled trial: Training paediatricians to follow guidelines for the management of acute gastroenteritis improves guideline adherence and reduces the duration of diarrhoea in young children

    • Joel S Tieder
    Evid Based Med 2010;15:3 83-84 doi:10.1136/ebm1073

  • Systematic review: There is a slight increase in incident diabetes risk with the use of statins, but benefits likely outweigh any adverse effects in those with moderate-to-high cardiovascular risk

    • Lokpal Bhatia,
    • Christopher D Byrne
    Evid Based Med 2010;15:3 84-85 doi:10.1136/ebm1075

Treatment

  • Cohort: Standard medical care does not offer sufficient relief of non-specific chest pain leading to additional diagnostic testing of no clinical benefit

    • Clare J Taylor,
    • Richard J McManus
    Evid Based Med 2010;15:3 86-87 doi:10.1136/ebm1061

  • Randomised controlled trial: Extending transdermal nicotine therapy from 8 to 24 weeks increases point-prevalence abstinence at 24 but not 52 weeks

    • Anne M Joseph
    Evid Based Med 2010;15:3 87-88 doi:10.1136/ebm1064

  • Randomised controlled trial: Low-carbohydrate ketogenic diet and the combination of orlistat with a low-fat diet lead to comparable improvements in weight and blood lipids, but LCKD more beneficial for blood pressure

    • Christopher D Gardner
    Evid Based Med 2010;15:3 91-92 doi:10.1136/ebm1065

  • Case control: The use of diuretics plus calcium channel blockers for hypertension may be associated with a higher risk of myocardial infarction but not stroke compared with the combination of diuretics plus β blockers

    • Rhonda M Cooper-DeHoff,
    • Carl J Pepine
    Evid Based Med 2010;15:3 92-93 doi:10.1136/ebm1067

  • Randomised controlled trial: Targeted, immediate antibiotics following a positive dipstick test may be the optimal management strategy

    • Kurt G Naber
    Evid Based Med 2010;15:3 90-91 doi:10.1136/ebm1068
    Editor's Choice

  • Randomised controlled trial: Catheter ablation treatment for paroxysmal atrial fibrillation results in a longer time to treatment failure than anti-arrhythmic drugs and improves quality of life

    • Nassir F Marrouche
    Evid Based Med 2010;15:3 88-89 doi:10.1136/ebm1072

Prevalence

  • Cross sectional study: Reliance on self-reporting underestimates pregnancy smoking rates in Scotland, with more than 2400 pregnant smokers estimated to be missed each year

    • Van T Tong,
    • Patricia M Dietz,
    • Lucinda J England
    Evid Based Med 2010;15:3 94-95 doi:10.1136/ebm1053

  • Retrospective cohort study: Specialist visits (urologist, radiation oncologist, medical oncologist) are strongly associated with treatment received for prostate cancer in the USA

    • Matthew R Cooperberg
    Evid Based Med 2010;15:3 95-96 doi:10.1136/ebm1074

Prognosis

  • Cohort: Interventions to improve secondary prevention after stroke are needed: adherence to prescribed preventative drugs after stroke declines rapidly during the first 2 years after hospital discharge

    • Steven R Erickson,
    • Kim A Eagle
    Evid Based Med 2010;15:3 97-98 doi:10.1136/ebm1063

Purpose and procedure

  • Purpose and procedure

    Evid Based Med 2010;15:3 99-100 doi:10.1136/ebm.15.3.e1

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