Table of contents

Therapeutics

• Systematic review: Angina relief with percutaneous coronary intervention versus medical therapy for chronic stable angina (22 June, 2010)

  Dmitriy N Feldman
• Randomised controlled trial: Aspirin prophylaxis (100 mg daily) does not improve cardiovascular outcomes compared to placebo in asymptomatic individuals with incidental low-ankle brachial index (8 June, 2010)

  S Marlene Grenon, Michael S Conte
• Systematic review: Meta-analysis of RCTs finds that increasing consumption of polyunsaturated fat as a replacement for saturated fat reduces the risk of coronary heart disease (3 August, 2010)

  Lee Hooper
• Systematic review: Available evidence points to low effectiveness of influenza vaccines for older people (22 June, 2010)

  Lone Simonsen
• Pragmatic randomised controlled trial: Advanced practice nurses achieve results equal to or better than those of GPs in cardiovascular risk management in primary care (8 June, 2010)

  Christianne L Roumie, Russell L Rothman
• Randomised controlled trial: An ‘e-Nudge’ electronic reminder system that highlights individuals at raised cardiovascular risk encourages GPs to improve the collection of patient cardiovascular risk factor data (17 June, 2010)

  David W Bates
• Systematic review: Computer reminders to clinicians during routine activities produce only small improvements in adherence to processes of care: median improvement 4.2%, IQR 0.8–18.8% (8 June, 2010)

  Tim A Holt
• Systematic review: Muscle cramps: quinine derivatives likely to be effective but not recommended for routine use due to toxicity; vitamin B complex, naftidrofuryl and calcium channel blockers possibly effective (8 June, 2010)

  Gavin Young
• Randomised controlled trial: Adding subcutaneous liraglutide to metformin reduces HbA1c more than adding oral sitagliptin in patients whose type 2 diabetes is poorly controlled with metformin alone (7 July, 2010)

  Vivian Fonseca, Cyrus Desouza, Amna N Khan
• Randomised controlled trial: The 23-valent polysaccharide vaccine prevents pneumococcal pneumonia and reduces associated mortality in nursing home residents in Japan (8 June, 2010)

  Mark Loeb
• Multicentre randomised controlled trial: Cognitive behavioural therapy shown to be an effective and low cost treatment for subacute and chronic low-back pain, improving pain and disability scores in a pragmatic RCT (8 June, 2010)

  Jonathan C Hill, Nadine E Foster, Elaine M Hay
• REDUCE Randomised controlled trial: Dutasteride reduces incident prostate cancer in men after negative prostate biopsy (8 June, 2010)

  Andrew Vickers
• Systematic review: No evidence for switching antidepressants in treatment-resistant depressed patients (8 June, 2010)

  Michael E Thase
• Systematic review: Tamoxifen, raloxifene and tibolone decrease risk of invasive breast cancer in healthy women but increase risk of thromboembolism (tamoxifen, raloxifene), endometrial cancer (tamoxifen) or stroke (tibolone) (3 August, 2010)

  Victor G Vogel