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Randomised controlled trial
Intensive lowering of systolic blood pressure to a target of less than 120 mm Hg has no effect on the rate of fatal and non-fatal major cardiovascular events in high-risk patients with type 2 diabetes

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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure recommends a blood pressure (BP) treatment goal of <130/80 mm Hg for patients with diabetes and hypertension.1 This goal was derived from observational data.2 3 The BP arm of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial prospectively addressed whether this lower BP further reduced cardiovascular events in high-risk patients with type 2 diabetes.


ACCORD was a prospective, open-label, randomised trial that enrolled 10 251 patients at high-cardiovascular risk and type 2 diabetes. Of these, 4733 patients were randomised to either intensive (goal systolic BP (SBP) <120 mm Hg) or standard (goal SBP <140 mm Hg) control in a two-by-two factorial design. High risk was defined as a …

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