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  • Tricyclic antidepressants reduce frequency of tension-type and migraine headaches compared with placebo, and intensity of headaches compared with SSRIs, but cause greater adverse effects

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Therapeutics
Systematic review
Tricyclic antidepressants reduce frequency of tension-type and migraine headaches compared with placebo, and intensity of headaches compared with SSRIs, but cause greater adverse effects

https://doi.org/10.1136/ebm1176

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    Footnotes

    • Competing interests PDM has received support from Merck Serono, Novartis and Bayer Schering to attend conferences.