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Randomised controlled trial
Morning-only polyethylene glycol preparation for afternoon colonoscopy is superior to traditional evening-before preparation
  1. Suryakanth R Gurudu
  1. Division of Gastroenterology, Mayo School of Medicine, Scottsdale, Arizona, USA
  1. Correspondence to Suryakanth R Gurudu
    Division of Gastroenterology, Mayo Clinic in Arizona, Mayo School of Medicine, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA; gurudu.suryakanth{at}mayo.edu

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Context

Colonoscopy is a valuable diagnostic and therapeutic tool in colon cancer screening and prevention. Earlier studies have reported higher failure rates and lower adenoma detection rates among patients undergoing colonoscopy in the afternoon,1 2 and poor bowel preparation is considered to be the main cause for these results.2 3 Inadequate bowel preparation can result in longer procedure time, missed lesions and reduced screening intervals, thereby increasing cost and complications. Though there are several factors implicated in successful completion of a colonoscopy, quality of bowel preparation and timing of colonoscopy are considered two modifiable factors4 5 to improve successful completion. Therefore investigators in this study performed a randomised endoscopist-blinded study to compare the efficacy of bowel cleansing with one gallon (4 litres) polyethylene glycol (PEG) in the morning of an afternoon colonoscopy, with that of traditional evening-before regimen.

Methods

This is a prospective randomised endoscopist-blinded study in which investigators compared the bowel cleansing …

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