Multicentre trial in people with arthritis finds increased risk of clinically significant gastrointestinal events with diclofenac plus omeprazole compared with celecoxib

Alaa Rostom

doi:10.1136/ebm1196

Article metrics

Therapeutics

Randomised controlled trial

Multicentre trial in people with arthritis finds increased risk of clinically significant gastrointestinal events with diclofenac plus omeprazole compared with celecoxib

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	Abstract	Full	Pdf
Jul 2011	145	20	37
Aug 2011	206	35	57
Sep 2011	121	11	19
Oct 2011	42	2	4
Nov 2011	46	1	6
Dec 2011	42	4	4
Jan 2012	28	5	13
Feb 2012	14	1	1
Mar 2012	26	4	6
Apr 2012	15	3	2
May 2012	13	3	2
Jun 2012	10	1	0
Jul 2012	8	0	0
Aug 2012	16	1	0
Sep 2012	24	2	3
Oct 2012	26	0	2
Dec 2012	0	1	1
Feb 2013	0	1	2
Mar 2013	0	0	2
Apr 2013	0	0	1
May 2013	0	2	1
Jun 2013	6	0	0
Jul 2013	7	1	1
Aug 2013	7	0	1
Sep 2013	6	1	0
Oct 2013	6	0	4
Nov 2013	6	1	1
Dec 2013	5	0	0
Jan 2014	3	0	0
Feb 2014	4	0	0
Mar 2014	4	0	1
Apr 2014	20	0	1
May 2014	1	0	0
Jun 2014	2	0	1
Jul 2014	5	0	0
Sep 2014	3	1	0
Oct 2014	7	2	1
Nov 2014	8	0	0
Dec 2014	3	0	0
Jan 2015	6	0	1
Feb 2015	9	0	0
Mar 2015	9	0	1
Apr 2015	10	0	0
May 2015	6	0	1
Jun 2015	6	1	5
Jul 2015	6	0	0
Aug 2015	2	3	1
Sep 2015	12	0	0
Oct 2015	1	0	0
Nov 2015	6	0	0
Dec 2015	20	0	2
Jan 2016	15	0	0
Feb 2016	8	0	0
Mar 2016	4	2	2
May 2016	21	0	0
Jun 2016	3	0	0
Jul 2016	9	1	1
Aug 2016	10	0	0
Sep 2016	13	0	0
Oct 2016	12	0	1
Nov 2016	9	0	0
Dec 2016	13	0	0
Jan 2017	21	0	0
Feb 2017	7	0	0
Mar 2017	12	1	1
Apr 2017	10	0	0
May 2017	15	1	1
Jun 2017	9	0	0
Jul 2017	24	0	0
Aug 2017	10	0	0
Sep 2017	16	0	0
Oct 2017	29	0	0
Nov 2017	30	0	0
Dec 2017	38	0	0
Jan 2018	9	0	0
Feb 2018	14	0	0
Mar 2018	26	1	0
Apr 2018	16	2	1
May 2018	30	1	1
Jun 2018	25	0	0
Jul 2018	8	0	0
Aug 2018	18	0	0
Sep 2018	6	0	0
Oct 2018	17	1	1
Nov 2018	37	0	0
Dec 2018	20	0	0
Jan 2019	16	0	0
Feb 2019	10	0	1
Mar 2019	6	0	0
Apr 2019	5	0	0
May 2019	2	0	0
Jun 2019	4	0	0
Jul 2019	20	2	0
Aug 2019	8	0	0
Sep 2019	7	0	0
Oct 2019	32	5	1
Nov 2019	9	0	0
Dec 2019	19	0	0
Jan 2020	13	0	0
Feb 2020	19	0	0
Mar 2020	8	0	0
Apr 2020	18	0	0
May 2020	12	0	0
Jun 2020	13	0	0
Jul 2020	27	1	3
Aug 2020	4	0	1
Sep 2020	26	0	0
Oct 2020	14	0	0
Nov 2020	14	0	0
Dec 2020	12	0	0
Jan 2021	12	0	0
Feb 2021	35	0	1
Mar 2021	8	0	0
Apr 2021	10	0	0
May 2021	2	0	0
Jun 2021	0	0	2
Aug 2021	3	2	0
Oct 2021	13	2	0
Nov 2021	19	0	0
Dec 2021	27	3	0
Jan 2022	12	0	0
Feb 2022	14	0	0
Mar 2022	56	0	0
Apr 2022	37	8	5
May 2022	46	1	1
Jun 2022	49	1	0
Jul 2022	19	0	0
Aug 2022	43	0	0
Sep 2022	34	1	0
Oct 2022	41	1	0
Nov 2022	19	0	0
Dec 2022	10	0	0
Jan 2023	3	0	0
Feb 2023	60	0	0
Mar 2023	4	0	0
Apr 2023	18	0	0
May 2023	13	0	0
Jun 2023	3	0	0
Jul 2023	32	0	0
Aug 2023	2	0	0
Sep 2023	10	0	0
Oct 2023	18	0	0
Nov 2023	23	0	0
Dec 2023	17	1	0
Jan 2024	6	0	0
Feb 2024	10	0	0
Mar 2024	18	0	0
Total	2606	145	209

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