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Cohort study
Women with cytologically atypical glandular cells are at increased risk of developing gynaecological malignancy
  1. Julie Ann Francis
  1. Department of Obstetrics & Gynaecology, Kingston General Hospital, Queen's University, Kingston, Ontario, Canada
  1. Correspondence to Julie Ann Francis
    Department of Obstetrics & Gynaecology, Kingston General Hospital, Queen's University, Victory 4, Kingston, ON K7L 2V7, Canada; julie.francis{at}queensu.ca

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Context

Cervical screening is a highly effective way to reduce the rate of cervical cancer, which is one of the leading causes of death in young women.1 The 2001 Bethesda System divides premalignant glandular lesions into atypical glandular cells (AGC), AGC favour neoplasia and adenocarcinoma in situ. Screening guidelines have typically assigned higher priority to these lesions because of their association with increased rates of gynaecologic malignancy.2 The Taiwanese annual cervical screening programme was launched in 1995, and investigators have analysed this database in order to better categorise the risks associated with AGC.

Methods

This is a large retrospective cohort trial of Taiwanese …

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