Statistics from Altmetric.com
Vasomotor symptoms (VMS – hot flashes, night sweats) are considered the hallmark of the menopausal transition and early postmenopausal years; these symptoms affect 60–90% of women during this time period and quite often result in significant discomfort and impaired quality of life (QOL). Mechanistically, the occurrence of VMS is attributed to a malfunction or disruption within complex temperature circuits in charge of thermoregulation. Existing evidence suggests that these circuits are at least in part modulated by oestrogen and monoamine systems – that is, serotonin, norepinephrine. In the aftermath of the Women's Health Initiative Study, physicians and patients became more reluctant to pursue or remain adherent to hormone-based therapies, and a growing interest has been observed in the development …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.