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Randomised controlled trial
The combination of phentermine and topiramate is an effective adjunct to diet and lifestyle modification for weight loss and measures of comorbidity in overweight or obese adults with additional metabolic risk factors

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Footnotes

  • Competing interests LJA is a consultant, speaker and advisor and receives research support from Abbott, Amylin, Arena, BMIQ, GI Dynamics, GSK, Novo Nordisk, Orexigen, Vivus. CMA has participated on the advisory boards of Allergan, Amylin, Orexigin, Merck, Johnson & Johnson, Arena and Sanofi-Aventis, and has received research funding from Lilly, Amylin, Pfizer, Sanofi-Aventis, Orexigen, MetaProteomics and the Dr Robert C and Veronica Atkins Foundation.