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Non-steroidal anti-inflammatory drugs (NSAIDs) have been implicated in causing negative cardiovascular outcomes, particularly in coronary artery disease (CAD) patients who have had a prior myocardial infarction (MI). In fact, as Schjerning Olsen and colleagues point out, current guidelines give the rather nebulous recommendation that duration of NSAID therapy should be as short as possible in CAD patients.1
The study by Schjerning Olsen and colleagues seeks to characterise the association between NSAID treatment duration and risk of cardiovascular disease. Although selective cyclooxygenase 2 inhibitors (COX-2) such as rofecoxib and valdecoxib have received notoriety and …
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