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Randomised controlled trial
Tiotropium is superior to salmeterol in reducing frequency of exacerbations: but the effect of adding tiotropium to the combination of inhaled corticosteroid and long-acting β(2)-agonist remains unclear

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Footnotes

  • Competing interests RH has received research grants, consulting and speaking honoraria from AstraZeneca, Boehringer-Ingelheim, GlaxoSmithKline, Novartis, Nycomed.