Table of contents

Therapeutics

• Randomised controlled trial: Robustness, risk and responsivity in early language acquisition: a randomised trial of a low-intensity language promotion programme for slow to talk toddlers finds no effects on language or behavioural development (18 February, 2012)

  Catherine L Taylor
• Randomised controlled trial: Caudal epidural steroid injections no better than saline epidurals or sham injections for the treatment of chronic lumbar radiculopathy (20 December, 2011)

  Bradley Kenneth Weiner, Joseph Fernandez-Moure
• Systematic review and meta-analysis: Some oral antidiabetic medications may prevent Type 2 diabetes in people at high risk for it, but the evidence is insufficient to determine whether the potential benefits outweigh the possible risks (22 December, 2011)

  Andrew J Krentz
• Systematic review and meta-analysis: Oral ondansetron decreases vomiting, as well as the need for intravenous fluids and hospital admission, in children with acute gastroenteritis (22 December, 2011)

  Deborah A Levine
• Systematic review with meta-analysis: In irritable bowel syndrome, antispasmodics and antidepressants improve abdominal pain and global assessment and symptom scores, but there is no evidence for the effectiveness of bulking agents (22 March, 2012)

  Alexander C Ford
• Randomised controlled trial: In TIA or stroke patients with intracranial arterial stenosis, aggressive medical therapy was superior to percutaneous transluminal angioplasty and stenting for 30-day risk of further stroke or death (7 March, 2012)

  Tim Darsaut, Jean Raymond, Sylvain Lanthier
• Randomised controlled trial: Evening dosing of antihypertensive medications results in better blood pressure control and decreases cardiovascular morbidity and mortality in patients with Type 2 diabetes (22 December, 2011)

  Rajesh Mohandas, A Ahsan Ejaz