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The evidence that statins reduce both all-cause and cardiovascular disease mortality when used for both primary and secondary prevention is incontrovertible. However, recent meta-analyses of trials have also shown that statins increase risk of incident diabetes.1 ,2 Culver and colleagues who are from the Women's Health Initiative (WHI) have investigated the association between usage of different statins and incident diabetes in a large cohort of postmenopausal women to assess the balance of risks and benefits of statin treatment in this population.
The WHI included 161 808 postmenopausal women aged 50–79 years recruited in the USA between 1993 and 1998 in a trial of dietary modification, hormone replacement therapy (HRT) …
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