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Chest pain is the second-most common reason for visiting the emergency department (ED). Due to diagnostic uncertainty and medicolegal concerns, many such patients are admitted to undergo diagnostic evaluation to exclude acute coronary syndromes (ACS). The availability of a safe, rapid, non-invasive and highly accurate diagnostic test to exclude ACS has remained a holy grail in the ED.
A total of 1370 low-to-intermediate risk adult patients presenting to one of five EDs in the USA with chest pain and suspected ACS were randomised to coronary CT angiography (CCTA) or to standard care. Patients with …
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