Article Text
Prevention
Systematic review with meta-analysis
Among statin-treated patients, LDL, non-HDL and apoB cholesterol biomarkers were associated with increased risks of cardiovascular events
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Context
Each very-low-density lipoprotein and low-density lipoprotein (LDL) particle contains one molecule of apolipoprotein B (apoB). Increased numbers of cholesterol-depleted LDL particles are common in patients with hypertriglyceridaemia, premature vascular disease, obesity and type-2 diabetes mellitus and much in vitro and in vivo evidence indicates cholesterol-depleted LDL particles are at least as atherogenic as larger, more cholesterol-replete LDL particles.1 Nevertheless, …
Footnotes
Competing interests None.