Article Text

PDF
Randomised controlled trial
One iron pill a day keeps fatigue away?
  1. Pierre-Alexandre Krayenbuehl,
  2. Henriette Heinrich
  1. Division of Internal Medicine, University Hospital of Zurich, Zurich, Switzerland
  1. Correspondence to : Dr Pierre-Alexandre Krayenbuehl
    Division of Internal Medicine, University Hospital of Zurich, Zurich 8091 Switzerland; pierrea.krayenbuehl{at}usz.ch

Statistics from Altmetric.com

Commentary on OpenUrlAbstract/FREE Full Text

Context

Could an apple a day keep the doctor away? The world's first multicentre trial addressed this question and found that a simple treatment lacked effect in common cold.1 Can an iron pill a day keep fatigue away? Iron is one of the cornerstones of cellular function being key in haemoglobin and DNA synthesis, and influencing enzymatic activity and especially mitochondrial function. The supposed association between iron deficiency and fatigue is long standing and has so far been difficult to prove. Although fatigue in the context of iron-deficiency ‘anaemia’ is self-evident for every doctor, and notably, pathophysiologically easy to comprehend, fatigue associated solely with low iron stores in ‘non-anaemic’ patients is …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.