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  • Extensive scheduled CT and CEA follow-up are equivalent in detecting recurrent colorectal cancer that is surgically treatable with curative intent, and superior to minimal follow up

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Prevention
Randomised controlled trial
Extensive scheduled CT and CEA follow-up are equivalent in detecting recurrent colorectal cancer that is surgically treatable with curative intent, and superior to minimal follow up
  1. Stuart A Taylor
  1. Centre for Medical Imaging, University College London, London, UK
  1. Correspondence to: Professor Stuart A Taylor, Centre for Medical Imaging, University College London, 250 Euston Road, London NW1 2BU, UK; stuart.taylor1{at}nhs.net

https://doi.org/10.1136/eb-2014-101758

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    Commentary on: Primrose JN, Perera R, Gray A, et al; FACS Trial Investigators. Effect of 3 to 5 years of scheduled CEA and CT follow-up to detect recurrence of colorectal cancer: the FACS randomised clinical trial. JAMA 2014;311:263–70.OpenUrlCrossRefPubMedWeb of Science

    Context

    Recurrence after attempted curative colorectal cancer surgery remains problematic with up to 50% developing metastases by 5 years.1 More aggressive surgical approaches likely improve prognosis,2 and there is a reasonable assumption that early detection by intensive patient follow-up improves outcomes. Two meta-analysis suggest regular measurement of carcinoembryonic antigen (CEA) and CT scanning of the chest, abdomen and pelvis (CT CAP) may increase the number of patients with potentially curable recurrence.3 ,4 The aim of this trial was to provide evidence for the benefit or otherwise …

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    Footnotes

    • Competing interests None.