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While mortality rates from cardiovascular diseases—particularly ischaemic heart disease (IHD)—have been declining in Western countries, IHD still contributes a significant burden to individuals, healthcare systems and society.1 Therefore, IHD prevention efforts could have major impact on societal health. Given the widespread prevalence of IHD and IHD risk factors, population-focused public health strategies are needed, especially as the value of individual, high-risk programmes will be limited to the individuals directly targeted. The Inter99 randomised trial was designed to test a screening and lifestyle counselling programme to reduce individual-level IHD risk. After 5 years, the Inter99 intervention resulted in significant risk reduction. Jorgensen and colleagues report on a 10-year follow-up of the study to …