Table of contents

Therapeutics

• Review: Adjuvant tamoxifen reduces recurrence and improves survival in early breast cancer (1 April, 1999)
• Review: Killed whole-cell vaccines prevent cholera for 2 years (1 April, 1999)
• Clodronate reduced the incidence of bony and visceral metastases in patients with breast cancer and tumour cells in the bone marrow (1 April, 1999)
• Review: Calcium supplementation in pregnancy reduces high blood pressure and preeciampsia but not adverse fetal outcomes (1 April, 1999)
• Levonorgestrel was more effective than combined oral contraceptives for emergency contraception (1 April, 1999)
• 4 anticonvulsant drug regimens had similar efficacies for generalized convulsive status epilepticus (1 April, 1999)
• Integration of medical and social services for elderly people in the community reduced costs and the use of health services (1 April, 1999)
• A general practice—based conservative approach was effective for urinary incontinence in Women (1 April, 1999)
• Review: β-blockers benefit patients with chronic heart failure (1 April, 1999)
• Carotid endarterectomy had a modest benefit for 50% to 69% stenosis after TIA or nondisabling stroke and no benefit for < 50% stenosis (1 April, 1999)
• Review: Corticosteroid therapy does not reduce the rate of relapse in Crohn disease (1 April, 1999)
• Pravastation reduced cardiovascular events in older patients with myocardial infarction and average cholesterol levels (1 April, 1999)
• Budesonide increased remission rates more than mesalamine in active Crohn disease (1 April, 1999)
• Periodic blood transfusions reduced the risk for stroke in children with sickle-cell anaemia (1 April, 1999)
• Review: Anticholinergic drugs, some behavioural interventions, and the elimination of cow's milk are effective in infantile colic (1 April, 1999)
• Review: Cognitive behavior therapy is effective tor the chronic fatigue syndrome (1 April, 1999)