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https://doi.org/10.1136/ebm.4.6.210a

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    Terms used in therapeutics

    1. When the experimental treatment reduces the risk for a bad event:

    RRR (relative risk reduction): the proportional reduction in rates of bad events between experimental (experimental event rate [EER]) and control (control event rate [CER]) patients in a trial, calculated as |EER ­ CER|/CER and accompanied by a 95% confidence interval (CI).

    ARR (absolute risk reduction): the absolute arithmetic difference in event rates, |EER ­ CER|.

    NNT (number needed to treat): the number of patients who need to be treated to achieve one additional favourable outcome; calculated as 1/ARR, rounded up to the next highest whole number, and accompanied by its 95% CI.

    2. When the experimental treatment increases the probability of a good event:

    RBI (relative benefit increase): the increase …

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