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Therapeutics
Review: glucocorticoids improve symptoms of croup within 6 hours

https://doi.org/10.1136/ebm.5.2.41

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    (1999) BMJ 319, 595. Ausejo M, Saenz A, Pham B, et al.. The effectiveness of glucocorticoids in treating croup: meta-analysis.. Sep 4;. :. –600.
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 QUESTION: In children with croup, what is the effectiveness of glucocorticoids on croup severity, length of hospital stay, and need for additional interventions?

    Data sources

    Studies were identified by searching Medline (1966 to August 1997), EMBASE/Excerpta Medica (1974 to August 1997), and the Cochrane Library Controlled Trials Register. Authors of trials published in the past 5 years were contacted.

    Study selection

    Studies were selected if they were randomised controlled trials of glucocorticoids compared with placebo or another active treatment in patients with croup and if clinically relevant outcome measures were used (clinical score, length of hospital stay, or need for additional interventions).

    Data extraction

    Data were extracted on patient characteristics, details about the intervention and control, and outcomes. The main outcome measure was improvement from baseline croup score. Additional outcomes were length of stay in the hospital or emergency department, rate of hospitalisation, and …

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