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Evid Based Med 5:42 doi:10.1136/ebm.5.2.42
  • Therapeutics

Review: antibiotics have a slight beneficial effect on acute bronchitis

Antibiotics v placebo for outcomes of acute bronchitis measured by ≥4 trials

Outcomes Number of trials Weighted mean decrease (95% CI)
*Significant when pooled in units of standard deviation, but not significant in units of days.
†Heterogeneity existed among these studies. Results were not significant.
Days of purulent sputum 6 0.4 d (−0.1 to 0.8)*
Days of cough 4 0.5 d (−0.1 to 1.1)†
Days off work 6 0.3 d (−0.6 to 1.1)†

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