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Clinical prediction guide
A 2 factor model helped to rule out early stage necrotising fasciitis

https://doi.org/10.1136/ebm.6.3.96

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    (2000) J Am Coll Surg 191, 227. Wall DB, Klein SR, Black S, et al.. A simple model to help distinguish necrotizing fasciitis from nonnecrotizing soft tissue infection. . Sep;. :. –31.
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 QUESTION: How accurate is a 2 factor model in differentiating early stage necrotising fasciitis (NF) from other non-necrotising soft tissue infections (NNFs)?

    Design

    The model was derived by using data from a previous case control study, and a retrospective cohort study was used to validate the model.

    Setting

    A university medical centre in Torrance, California, USA.

    Patients

    Data from 42 patients (mean age 39 y, 81% men, 50% with NF and 50% with NNF) were used for the derivation set. Data from 359 patients (mean age 44 y, 77% men, 9% with NF and 91% with NNF) admitted to hospital between April 1998 and March 1999 with a primary diagnosis of NF or NNF infection at discharge were used for the validation set. More patients with NF had a history of hepatitis (19% …

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    Footnotes

    • Source of funding: not stated.

    • For correspondence: Dr C de Virgilio, Department of Surgery, Harbor-UCLA Medical Center, 1000 West Carson Street, Box 25, Torrance, CA 90509, USA. Fax + 1 310 782 1562.