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Evid Based Med 6:107 doi:10.1136/ebm.6.4.107
  • Therapeutics

Review: antiplatelet drugs reduce pre-eclampsia, preterm birth, and stillbirth or neonatal death

Antiplatelet drugs v placebo or no antiplatelet drug for women at risk for pre-eclampsia*

Weighted event rates
Outcomes at delivery Number of trials Antiplatelet Placebo RRR (95% CI) NNT (CI)
*Abbreviations defined in glossary; weighted event rates calculated from data in article.
Pre-eclampsia 27 6.8% 7.8% 15% (8 to 22) 100 (59 to 167)
Preterm birth 23 17.2% 18.6% 8% (3 to 12) 72 (44 to 200)
Stillbirth or neonatal death 30 2.5% 2.9% 14% (2 to 25) 250 (125 to >10 000)

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