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ADDITIONAL ARTICLES ABSTRACTED IN ACP JOURNAL CLUB

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The following articles are abstracted in the November/December 2001 issue of ACP Journal Club. The declarative title of each abstract as published in ACP Journal Club precedes the article citation.

Therapeutics

Recombinant human activated protein C reduced all-cause mortality in severe sepsis

Review: IV immunoglobulins reduce mortality in bacterial sepsis and shock

Continuous infusion of amphotericin B reduced mortality more than rapid infusion

Review: glycoprotein IIb/IIIa inhibitors reduce myocardial infarction and urgent vascularisation but increase bleeding in percutaneous coronary intervention

Parathyroid hormone decreased fractures and increased bone mineral density in postmenopausal women

Review: transcutaneous electrical nerve stimulation is not effective in chronic low back pain

Percutaneous transluminal coronary angioplasty and endarterectomy were both effective for carotid stenosis

Review: single dose and longer duration cardioselective β-blockers do not increase respiratory symptoms in reversible airway disease

Antireflux surgery may be more effective than low dose, but not high dose, omeprazole for gastroesophageal reflux disease

Omeprazole was better than H pylori eradication for preventing recurrent gastrointestinal bleeds in patients taking naproxen

Diagnosis

Review: magnetic resonance angiography detects lower extremity arterial disease in claudication or critical limb ischaemia

Prognosis

Women were at higher risk than men for a major bleed while taking warfarin for atrial fibrillation

Economics

Implantable defibrillator v amiodarone for longer survival after VF or VT

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