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Verbal advice plus an information leaflet reduced antibiotic use in acute bronchitis

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 QUESTION: In patients presenting with acute bronchitis, does verbal advice plus an information leaflet describing the uncertain value of antibiotics reduce antibiotic use more than verbal advice alone?

Design

Randomised (unclear allocation concealment*), blinded (clinicians and data collectors),* controlled trial with 4 weeks of follow up.

Setting

3 general practices in Nottingham, UK.

Patients

259 patients ≥ 16 years of age who had acute bronchitis (ie, illness for ≤ 21 d; main symptom of cough; ≥ 1 of sputum production, dyspnoea, wheeze, or chest discomfort or pain; and no alternative explanation) and were not receiving medical attention for an underlying disease, such as asthma, heart disease, or diabetes. 47 patients were judged to need antibiotics immediately. 212 …

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Footnotes

  • Source of funding: British Lung Foundation.

  • For correspondence: Dr J Macfarlane, Nottingham City Hospital, Nottingham, UK. john.macfarlane{at}tinyworld.co.uk.

  • A modified version of this abstract also appears in Evidence-Based Nursing.

  • * See glossary.

  • Calculated from data in article.