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ADDITIONAL ARTICLES ABSTRACTED IN ACP JOURNAL CLUB

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The following articles are abstracted in the November/December 2002 issue of ACP Journal Club. The declarative title of each abstract as published in ACP Journal Club precedes the article citation.

Therapeutics

A prophylactically implanted cardioverter defibrillator reduced all-cause mortality in myocardial infarction

Epidural anesthesia and analgesia did not reduce most comorbid outcomes in high-risk patients having major abdominal surgery

Review: oral glycoprotein IIb/IIIa inhibitors increase mortality and myocardial infarction

A split regimen of regular insulin at dinner and NPH insulin at bedtime reduced nocturnal hypoglycaemia in type 1 diabetes

Maintenance infliximab increased time to loss of response in active Crohn disease

Review: somatostatin analogues reduce blood products used in acute bleeding esophageal varices but do not reduce mortality

Review: antibiotic prophylaxis reduces mortality and bacterial infection in cirrhosis and gastrointestinal bleeding

Review: antifungal agents do not reduce mortality in neutropenia caused by chemotherapy or bone-marrow transplantation

Diagnosis

Review: magnetic resonance angiography is accurate for detecting high-grade carotid artery stenosis that is suitable for surgery

Magnetic resonance angiography had high specificity but moderate sensitivity for detecting pulmonary emboli

Review: oral antifungal drugs promote cure of fungal foot infections

Prognosis

Predictors of poor outcome in acute stroke included dependency before stroke, severe hemiparesis, and recurrent stroke

Clinical prediction guide

Arterial blood lactate measurements quickly identified risk for death from paracetamol (acetaminophen)-induced liver failure

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