Immediate v delayed antibiotics in children with acute otitis media by day 3§
| Outcomes in children with fever (temperature >37.5°C) or vomiting at diagnosis | Immediate antibiotics | Delayed antibiotics | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| Distress | 32% | 53% | 40% (16 to 57) | 5 (3 to 14) |
| Night disturbance | 26% | 59% | 56% (37 to 70) | 3 (2 to 5) |
| Outcomes in children without fever or vomiting | ||||
|---|---|---|---|---|
| §Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article. | ||||
| Distress | 15% | 19% | 21% (−45 to 57) | Not significant |
| Night disturbance | 20% | 27% | 26% (−22 to 55) | Not significant |
