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Evid Based Med 8:86 doi:10.1136/ebm.8.3.86
  • Therapeutics

Dexamethasone improved disability in acute bacterial meningitis

Dexamethasone v placebo for bacterial meningitis at 8 weeks‡

Outcomes Dexamethasone Placebo RRR (95% CI) NNT (CI)
‡Unfavourable outcome = score of 1–4 on the Glasgow Outcome Scale: death, vegetative state, severe disability, or moderate disability. Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
Unfavourable outcome 15% 25% 41% (7 to 63) 10 (5 to 73)
Death 7% 15% 52% (5 to 75) 13 (7 to 163)

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