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  • Review: depression, social isolation, and certain life events are associated with the development of coronary heart disease

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Aetiology
Review: depression, social isolation, and certain life events are associated with the development of coronary heart disease

https://doi.org/10.1136/ebm.8.6.189

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    (2003) Med J Aust 178, 272. Bunker SJ, Colquhoun DM, Esler MD, et al.. Stress and coronary heart disease: psychosocial risk factors.. ;. :. –6.
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 QUESTION: Are certain psychosocial risk factors (stressors) associated with the development and progression of coronary heart disease (CHD)?

    Data sources

    Reviews were identified by searching Medline, EMBASE/Excerpta Medica, and PsycINFO using 47 search terms to describe study design, outcomes, and stressors. Reference lists of reviews and personal files of the investigators were also searched.

    Study selection

    Reviews were selected if they were published in English in peer reviewed journals after 1979 and included prospective studies with ≥100 patients, and if CHD outcomes included myocardial infarction, myocardial revascularisation, and CHD death.

    Data extraction

    2 investigators independently assessed the quality of the selected reviews using a validated 7 point score. For reviews with a score ≥4, data were extracted on years covered, reviewers’ backgrounds, …

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